Agaricus Blazei Murill Polysaccharides

Botaniex provides Extract of Agaricus Blazei Mushroom in the following specifications.

*Customized specification available upon request.

Agaricus Blazei Mushroom

Agaricus blazei Murrill (ABM) popularly known as ‘Cogumelo do Sol’ in Brazil, or ‘Himematsutake’ in Japan, is a mushroom native to Brazil, and widely cultivated in Japan for its medicinal uses, so it is now considered as one of the most important edible and culinary-medicinal biotechnological species. It was traditionally used to treat many common diseases like atherosclerosis, hepatitis, hyperlipidemia, diabetes, dermatitis and cancer. In vitro and in vivo ABM has shown immunomodulatory and antimutagenic properties, although the biological pathways and chemical substances involved in its pharmacological activities are still not clear. The polysaccharides phytocomplex is thought to be responsible for its immunostimulant and antitumor properties, probably through an opsonizing biochemical pathway. Clinical studies are positive confirmations, but we are still at the beginning, and there are perplexing concerns especially relative to the content of agaritine. Argantine is a well-known carcinogenic and toxic substance in animals that must be completely and fully evaluated.

ABM as a functional food, which enjoyed great popularity for numerous high-quality bioactive nutrient components. In general, active metabolites can be isolated from ABM fruiting bodies, pure cultured mycelium, and submerged fermentation culture from mycelium and culture filtrate. There are differences in the content of biologically active substances in different parts of ABM (mycelia and fruit body) and between treatment methods (dry powder, hydro alcoholic extracts and fresh ABM).

Benefits of Agaricus Blazei Mushroom Extract

· Enhance Immune function

· Lowers blood glucose

· Anti-tumor and tumor preventative

· Anti-cancer

· Prolong life expectancy

· Anti-aging

· Protects liver and kidney

Mechanisms

The health care function of Agaricus Blazei Murrill is evidenced by the test results of several medical units in Japan. Agaricus Blazei polysaccharides can bind to many amino acids and are easily absorbed by the body's digestive organs. The 15 medicinal fungi that are recognized as effective against tumors, such as Ganoderma Lucidum, shiitake mushrooms, pine mushrooms, Agaricus Blazei, etc., have a common feature, that is, they contain anti-tumor active polysaccharides. According to research, the polysaccharide content of Ganoderma lucidum, which is called 'Immortal Mushroom', is 1.30g/100g, while the content of Agaricus Blazei polysaccharide is as high as 6.55g/100g, and its polysaccharide content is 5 times that of Ganoderma lucidum. More uniquely, Agaricus Blazei contains a structure of β (1-6)-D-glucan that rapidly increases immunity, which is not found in Ganoderma lucidum. At the same time, Agaricus Blazei contains β-D-glucan, a peculiar anti-tumor active substance that directly enhances the activity of phagocytic cells, macrophages and natural immune cells.

Agaricus Blazei has high nutritional and medicinal value. As a health food, it has sufficient theoretical basis and clinical trials for research and development and clinical trials of Agaricus Blazei.

Safety

Used in traditional and alternative medicine for its supposed anti-cancer effects, Agaricus mushrooms have not been assessed by sufficient high-quality clinical research to define safety and biological properties upon consumption as a food, dietary supplement, or drug. Preliminary research indicates Agaricus products may have toxic effects on liver function by inhibition of P450 enzymes, especially in people with ovarian cancer, and may cause allergic reactions.

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