Grape Seed Extract

Grapeseed-EX™ is Botaniex’s branded ingredient extracted from Grape Seed.

Latin Name	Vitis vinifera L.
Plant Family	Vitaceae
Part of Plant Used	Seed (Skin)

Molecular Structure

Benefits

• Traditional/Ethnobotanical uses

  OPC (Oligomeric Proantho Cyanidins) is found in grape seed and pine bark. OPC have been marketed in France for decades as treatment for venous and capillary disorders (eg, retinopathies, venous insufficiency, and vascular fragility). Red wine contains OPC, and when used in association with a nonatherogenic diet, may reduce the incidence of cardiovascular disease.

• Nutritional

  Grape seed oil contains nutritionally useful essential fatty acids and tocopherols (vitamin E). V. coignetiae also contains vitamins A, C, and F. Dietary grape seed tannins and procyanidins (polyphenol oligomers) also are reported.

• Antioxidant

  The antioxidant activity of grape seed extract has been tested clinically. It was shown that the extract elevated total antioxidant activity in the serum.

• Other uses

  Grape seed has been shown to have antibacterial activity, and to be a safe and effective hand-cleansing agent. Grape seed also is effective in the prevention of dental caries. Grape seed also may be cytoprotective (protects against cancer). Early studies show some promise, but more research needs to be done in order to fully understand the benefits of grape seed.

Safety

It is contraindicated in patients with known hypersensitivity to grape seed.

Dosage

For use as a general antioxidant much as you might use vitamin E or vitamin C, 50 mg of OPCs daily are sufficient. A higher dosage of 150 to 300 mg daily is generally used for treating specific diseases such as varicose veins.

Applications

It is clinically used to prevent and treat high cholesterol, atherosclerosis, gastric ulcers, etc., and as a raw material for food additives, cosmetics, health products and beverages.

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